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Such isomers can be obtained in substantially pure form by classical separation techniques and by stereochemically controlled synthesis.

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Suppression of Recurrent Genital Herpes in HIV─1-Infected Subjects: In HIV─1-infected subjects, frequently reported adverse reactions for VALTREX (500 mg twice daily; n = 194, median days on therapy = 172) and placebo (n = 99, median days on therapy = 59), respectively, included headache (13%, 8%), fatigue (8%, 5%), and rash (8%, 1%)?